This review article provides an analysis of cyclic variations in East Africa that indicate a catastrophic famine event. Using historical and contemporary data, we examine the cycles of drought and famine that have occurred in the region over the past centuries. Our analysis reveals that the frequency and severity of droughts and famines in East Africa have increased significantly in recent decades, with a clear cyclic pattern that suggests a looming catastrophic event in 2028-2035. We explore the underlying causes of these cycles, including climate change, population growth, and political instability, and consider the implications of our findings for future food security and humanitarian aid efforts in the region. Ultimately, this analysis highlights the urgent need for proactive measures to prevent and mitigate the impact of catastrophic famine events in East Africa.